清风藤属化学成分及药理活性研究进展

卜庆, 梁林富, 钟林静, 陈俊锟, 徐梦娟, 朱丽丽

中国药学杂志 ›› 2023, Vol. 58 ›› Issue (13) : 1157-1165.

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中国药学杂志
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中国药学杂志 ›› 2023, Vol. 58 ›› Issue (13) : 1157-1165. DOI: 10.11669/cpj.2023.13.001
综述

清风藤属化学成分及药理活性研究进展

  • 卜庆, 梁林富*, 钟林静, 陈俊锟, 徐梦娟, 朱丽丽
作者信息 +

Research Progress on the Chemical Constituents and Pharmacological Activities of the Genus Sabia

  • BU Qing, LIANG Lin-fu*, ZHONG Lin-jing, CHEN Jun-kun, XU Meng-juan, ZHU Li-li
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文章历史 +

摘要

清风藤属(Sabia)植物在我国资源丰富,约16个种、5个亚种、2个变种。该属多种植物被少数民族药物志收录。清风藤属化学成分包括五环三萜、生物碱、黄酮、苯丙素类、其他苯衍生物类、脂肪酸和烷烃类等,具有护肝肾、降血糖与血脂、治疗类风湿关节炎、镇痛、抗流感病毒、催产等多种功效。本文对近30年来国内外相关文献进行归类、分析和总结,综述了清风藤属的230个化学成分及其药理活性与临床应用,旨在为该属植物的进一步研究与开发提供科学依据。

Abstract

The plants belong to the genus Sabia distribute widely in China, and they can be divided into ca. 16 species, 5 subspecies, and 2 varieties. A variety of Sabia plants have been recorded in different medicinal literatures. The chemical constituents of this genus contain pentacyclic triterpenes, alkaloids, flavonoids, phenylpropanoids, other benzene derivatives, fatty acids and alkanes, which exhibit multiple functions such as liver/kidney-protective, blood sugar/lipid-lowering, treating rheumatoid arthritis, analgesic, anti-influenza virus, and oxytocic effects. In this paper, 230 compounds reported in recent 30 years and their pharmacological activities are reviewed, and the purpose is to provide a scientific basis for further research, development and utilization of this genus.

关键词

清风藤属 / 生物碱 / 五环三萜 / 黄酮 / 抗流感病毒

Key words

Sabia / alkaloid / pentacyclic triterpene / flavonoid / anti-influenza virus

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卜庆, 梁林富, 钟林静, 陈俊锟, 徐梦娟, 朱丽丽. 清风藤属化学成分及药理活性研究进展[J]. 中国药学杂志, 2023, 58(13): 1157-1165 https://doi.org/10.11669/cpj.2023.13.001
BU Qing, LIANG Lin-fu, ZHONG Lin-jing, CHEN Jun-kun, XU Meng-juan, ZHU Li-li. Research Progress on the Chemical Constituents and Pharmacological Activities of the Genus Sabia[J]. Chinese Pharmaceutical Journal, 2023, 58(13): 1157-1165 https://doi.org/10.11669/cpj.2023.13.001
中图分类号： R284   

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国家自然科学基金项目资助(41876194)
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